What suspension? Front or rear? Either way it's dumber than Clinton saying he hates ranger's.
The F150s have IFS, same as the ranger's. You couldnt affor to make the front of an F150 work on a ranger and make it plausible. As for the front of the F250's and 350's is either a D50 or D60 straight axle. Sure you could do it. It's called an SAS, people do it every day.
As for the rear, the spring rate of those heavier trucksr will make your truck ride like an f-ing dump truck first of all. Second, you would have to COMPLETELY tear all the hardware off your frame to add all new hangers and shackles (which means drilling holes in your frame). THIRD you MIGHT gain 2-3 inches of lift when all your dumbass coulda done was gone out and got a fu cking add a leaf for a hundredth of a cost. Yes I said (1/100). FOURTH the leaf springs are way too long for your truck so your hangers would be out at the end of the frame. FIFTH you wouldnt be able to flex worth ****. SIXTH, you would need to weld wider spring perches on your axles to accomadate your wider springs.
80-96 2wd F150s have 2.5" leaf springs as do the newer 4x4 F150s, but your still in the same boat you were in w/ the hangers. Shackles are the same. It's pointless.